Non-Cellular Applications of Regenerative Medicine Treatments

Non-Cellular Applications of Regenerative Medicine Treatments

The goal of regenerative medicine procedures in general is to restore structure and function of damaged tissues and organs, and that is a very important point that distinguishes regenerative medicine procedures from conventional medicine procedures.  For example, we are not trying to just stop pain or to improve a joint through lubricating it or administering an anti-inflammatory medication.  The goal of the regenerative treatment is to restore the normal structure and function of the damaged tissue.

I previously discussed what are commonly referred to as stem cell treatments, which is a cellular regenerative medicine treatment, and now I am going to talk about non-cellular regenerative medicine treatments.  The difference is that non-cellular treatments do not contain cells.  Some of these treatments are cellular products such as proteins, but they are not cells.  That’s the difference between the two types of treatments, but the mechanism of actions and the treatment goals are very similar.  More specifically, the goal is the same and the action is similar.

It is very important for a doctor to be well-versed in both non-cellular and cellular treatments in order to be able to determine which specific treatment is more likely to help a specific patient for a specific condition.  This is why we call what we do personalized precision medicine.

I could use one of a number of non-cellular or cellular treatments to address a very similar condition in different patients.  One might ask, why are you using a different treatment for the same condition?  The reason is that everybody is different.  Everybody responds differently to the same treatment, and every person’s condition is unique.  Take high blood pressure as an example.  We all know that there are many blood pressure medications on the market.  If every medication works the same on every person, we would only need one blood pressure medication.   So, part of my job is to determine what treatment is most likely to help a specific patient for his or her specific condition.

Let’s start with oxygen ozone injection therapy which is a non-cellular regenerative treatment.  Oxygen ozone injection therapy is an extremely powerful regenerative medicine treatment.  It helps cells increase in number, which is called proliferation, by favorably influencing the redox system, which controls the cell cycle.  It also has multiple other properties such as increasing oxygen delivery to tissues and reducing inflammation in the body.  I have had a lot of successes using this injection therapy treating patients with disc herniations, joint pain, sports injuries and muscle spasm because of these unique properties.  Oxygen ozone can also be used to stimulate hair follicles to reproduce more hair and thicker hair by the same mechanisms that I described above.

Another non-cellular product with regenerative properties is exosomes.  Exosomes are an extremely fascinating cellular excretion product.  Exosomes are vacuoles that are excreted by cells which contain messenger RNA, micro RNA, and proteins. They are very powerful in activating the body’s own stem cells to help rejuvenate and repair damaged structures.  For example, exosomes can potentially stimulate repair of damaged cartilage, skin and nervous tissue which is a very powerful non-cellular regenerative repair mechanism within our body’s own amazing ability to heal.

A2M is another powerful non-cellular regenerative medicine treatment.   A2M is a protein that is naturally found in our body which can be concentrated and injected into various structures such as joints and discs.  A2M will capture and deactivate proteins that destroy cartilage.  It is a very important treatment if cartilage is being destroyed in a joint or in a disc since A2M can stop the process.  It also has growth factor binding sites, so it has regenerative properties.

These are some of the many treatments with non-cellular regenerative medicine.   Since I wrote a previous blog discussing cellular regenerative medicine treatments, I won’t go into it again.  The most important point, as I discussed above, is for a doctor to be well versed in all types of regenerative medicine treatments in order to be able to determine which of these non-cellular or cellular treatments are most appropriate for a specific patient in order to give the patient the best chance of healing.

PodCast: Non-Cellular Treatments in Regenerative Medicine

Below you will find an easy to read transcript of Dr. Warren Bleiweiss’ podcast interview. You can listen to the podcast or simply read the easy to follow transcript below. Enjoy!

In this podcast, Dr. Bleiweiss further discusses regenerative medicine, with a focus on non-cellular treatments.

 

Click the link above to listen to Dr. Warren Bleiweiss’ new podcast interview.  You can also read a full transcript below.  Enjoy!

 

Podcast Interview:

 RC: Hello everyone, this is Liz Harvey coming to you from our studios in New York City where we are dedicated to bringing you top quality advice from many of the leading expert professionals across the U.S.

In today’s episode, we are speaking with Dr. Warren J. Bleiweiss about the exciting field of regenerative medicine. He is a graduate of New York University School of Medicine and is Board Certified in both Anesthesiology and Pain Management.  His long list of accomplishments includes leadership experience as a hospital anesthesiology department director, the inventor of a patented medical device, and the founder of one of the first multi-disciplinary pain management centers in New Jersey.

Dr. Bleiweiss also pioneered the treatment of oxygen ozone disc injection therapy in the United States, which is a powerful regenerative treatment. He has also been successfully treating patients for over 30 years. Dr. Bleiweiss specializes in minimally invasive alternative treatments that heal patients without surgery or potentially harmful medications. His treatment protocols are specifically designed to activate the body’s innate ability to recover and regenerate. His practice has been producing excellent results by utilizing these alternative methods.

We previously discussed oxygen ozone treatments with Dr. Bleiweiss. Today we are focusing on other aspects of regenerative medicine, and we are discussing non-cellular treatments in regenerative medicine.

Hello, Dr. Bleiweiss. How are you today?

Dr. Warren Bleiweiss: I’m great, thank you.

RC: Thanks again for joining me.

Since you keep up with and stay on top of the new developments in the field of regenerative medicine, I would like to ask you about non-cellular treatments in regenerative medicine. Could you please give us a brief overview?

Dr. Warren Bleiweiss: Yes, I’d be very happy to. I want to start by briefly mentioning that I discussed cellular regenerative treatments, which are commonly known as stem cell treatments, in a previous interview. If anybody is interested in learning a little bit more about those treatments, I’d encourage them to listen to that interview.

By contrast, non-cellular regenerative medicine treatments are biological agents, but they do not contain cells. The goal of regenerative medicine with stem cells and non-cellular treatments is the same. The goal is the same. It’s to restore structure and function of damaged tissues and organs. The agents are different because the non-cellular treatments do not contain cells, but they are biologic agents. These biologic agents activate the body’s own repair system, which again, will help regenerate damaged tissue and restore structure and function. There are many, many, many types of non-cellular regenerative medicine treatments. I’m going to limit this discussion to four types of non-cellular treatments.

The first is exosomes, which I find an extremely, extremely fascinating topic. I could talk about exosomes for hours, but I’m not going to do it today. Exosomes are tiny vacuoles. They’re excreted by cells, so they’re cellular excretion products. They’re not cells themselves because they don’t reproduce, but they’re cellular excretion vesicles. They contain, among other things, messenger RNA, microRNA, proteins. I can’t get into a whole discussion now about what actually is a messenger RNA versus a microRNA, but there’s plenty of information on the internet regarding these things. They could be used in every aspect of regenerative medicine. They have amazing regenerative and modulating properties.

Another potent regenerative medicine non-cellular treatment is oxygen ozone injection therapy. Oxygen ozone injection therapy, it has multiple actions, but one of the things that it does is it works through what’s known as the redox system. The redox system controls the cell cycle. The cell cycle has to do with when a cell decides to divide and create a new cell. In the proper doses, oxygen ozone injection treatments can induce cells to reproduce, to divide, to increase their number. It also vastly improves oxygen delivery to tissue.

Another treatment is A2M. A2M stands for alpha-2-macroglobulin. Alpha-2-macroglobulin is a very large molecule that is produced by the liver and circulates in our blood. It actually captures and deactivates enzymes that destroy cartilage, and joints, and discs. You might wonder why if it’s in our blood, why is that a treatment. The reason is that once a disc is destroyed or is in the process of being destroyed, and once a joint is in the process of being destroyed, the blood supply is compromised. The A2M from our body cannot get into these structures in the proper doses to actually switch off these destructive enzymes. By isolating the A2M and concentrating it, and introducing it into a disc or a joint, it’s a very powerful regenerative medicine tool.

The last one I want to mention is PRP. PRP has been around for a very long time. It contains many growth factors. It is a regenerative treatment. PRP is very complicated though because there are many different types of PRP. A lot of clinicians do not quite understand that the preparation of the PRP is very important. Now, I’m not knocking clinicians. I’m sure there are a lot of very fine clinicians who fully understand this topic, but there are also a lot of places that you come in and everybody gets the same PRP. It’s like a one size fits all. All PRP is not the same. I want to stress that. Depending on the machinery that’s used to spin down the platelets, the fraction that is withdrawn from the aliquot that is spun down, and how it’s administered, there’s many factors that determine whether it’s a regenerative type of PRP, or whether it’s a pro-inflammatory type or PRP, or whether it has a combination of both. It is a powerful tool, but it has to be fully understood and it has to be used properly.

These are just some of them. Like I said, there are so many treatments. It’s a fascinating field. I just gave you a brief overview of some of the most common types of non-cellular regenerative treatments.

What conditions can be treated with non-cellular applications of regenerative medicine?

Dr. Warren Bleiweiss: Again, there are many, many conditions that could be treated. I’m going to mention four conditions that I treat with these non-cellular regenerative medicine treatments, and that they’re very effective in treating. I want to come back to the difference between cellular and non-cellular after I mention these four treatments and discuss how we make a decision on what product to use.

These treatments are very effective for osteoarthritis of joints, which we all develop through normal aging and wear and tear. It could be of the shoulder, the hips, the knees. All of us to varying degrees develop these conditions. Sometimes it’s severe, sometimes it’s not severe. Sometimes it’s more prevalent in a hip or a knee in one individual, and sometimes in another joint in another individual. These treatments are very effective in helping restore structure and function to these damaged joints. Hair loss is also something that is treated with non-cellular regenerative medicine. It’s very effective in inducing follicles that are still active to increase the number of hairs and increase the thickness of the hair. It’s very good at treating aging of the skin. I’ve mentioned this before with cellular treatments, it’s not going to get rid of all your wrinkles. I’m not suggesting you have wrinkles. I’ve never met you. I’m just saying if somebody does have wrinkles, it’s not going to get rid of all the wrinkles, but it will rejuvenate the skin.

I just want to take a step back. It’s not altering the normal skin. You could get rid of wrinkles by injecting substances into the wrinkle like Restylane, I believe it’s called. I don’t do those treatments. You go to a dermatologist, they inject a substance into the wrinkle, or you could have Botox. There are other treatments. These things alter the anatomy. It’s not working with your own body’s healing system. Yes, you could puff up a wrinkle so you can’t see it, but what I’m talking about is working with your body’s innate ability to heal the damage that has occurred to our skin over time through various things, for example, sunlight, ultraviolet light from the sun. No matter how much suntan lotion we slather on ourselves, we do over time get exposure to ultraviolet light, and we do get damage from that.

Also, declining mental function. At the risk of repeating myself multiple times, I do want to, again, say that I’m not suggesting that you could take someone with severe dementia and give them these treatments and they’re going to be like new, but they are extremely effective. Many clinicians have reported effectiveness in improving cerebral function, dementia, or Alzheimer’s, particularly in the early stages.

The other thing I wanted to mention, and I talked about this in the beginning, is that I have discussed treatment of these issues with stem cells. Now I’m discussing it with non-cellular treatments. Someone listening to me might think, “Well, why are you saying stem cells could treat this and also non-cellular things could treat it? It’s very confusing.” The answer is it’s not confusing, it’s scientific. There is a reason why various treatments work better for different people and different conditions.

For example, let’s talk about knee pain and joint problems. Not every joint problem is the same. There are a lot of different joint problems that cause knee pain, and not every individual is the same. My job, one of the most important things in my job is to assess each individual personally and to determine which treatment is the best treatment for their condition. I will determine whether somebody, for example, might need stem cells to treat their knee joint, or they might need ozone to treat their knee joint, or exosomes. These are decisions that I make based on the individual person, what their medical condition is, their state of health, what their specific joint condition is, and other factors that I determine. That’s why we call this personalized precision medicine.

The other thing that I’ve mentioned in the past but I’ll mention it again is it’s very important for a physician to be fluent in performing all of these procedures and to understand the different types of treatments that are available because only then can you determine what is the best treatment for an individual. If I’m going in for a treatment for arthritis in my knee, for example, and stem cells could help and ozone could help, they both could help, I want to know which one has a better chance of helping. If one has a 60% chance of helping and one has an 80% chance of helping, for my specific condition, I have to reiterate that. This is not one treatment fits all. This is for my specific condition. I want the one that is going to have an 80% chance of helping me, and that’s what I do.

How do you evaluate a patient to determine if they are a candidate for one of these procedures?

Dr. Warren Bleiweiss: This segues very nicely into what I was just discussing. It’s the most important part of the treatment, and that’s the initial evaluation. I’ve said this in previous interviews. I evaluate every patient myself. I perform a history. I look at the labs. I look at the imaging. I sometimes order additional labs if I feel they’re necessary. I do a physical examination. That’s really the only way to evaluate a patient to determine if they’re a candidate for one of these procedures.

Could you walk us through what a typical patient would experience when they have a non-cellular regenerative medicine procedure?

Dr. Warren Bleiweiss: Yes, I’d be happy to. As we discussed with the cellular treatments in a previous interview, it’s essential to assure that a patient is in optimal health before the treatment so they’ll have the best chance of effective healing. That is a very, very important aspect of this treatment. With non-cellular treatments, preparing the patient is different than with cellular treatments. I’m not going to get too involved in the cellular treatments, which are stem cell treatments as we discussed, because I discussed it in detail. Those cells are living cells.

The way the patient is prepared is typically different than the non-cellular treatments. For example, when I discussed the stem cell treatments, I indicated that it is not appropriate to do the evaluation and the treatment on the same day and just send the patient home. There is a specific protocol to get the body ready for the stem cells and to nurse the patient along through the treatment process and the post-treatment process.

With non-cellular treatments, because they’re not living cells, certain treatments, not all, can be administered the day of the initial consult. For example, treating hair loss with ozone, that could be done the first day I see a patient typically. There might be other issues that I’m not going to get into, all of the little minute details. Typically, if a patient comes in for treatment with ozone injections for hair loss, that could be done on the same day. I will make that decision. Again, the most important part of deciding what treatment to do and how the patient is prepared for the treatment is the initial evaluation, which includes a careful history, a physical examination, and review of the testing. Again, as I discussed earlier, I’m the one who does that evaluation, and I’m the one who makes the decision. Then I discuss it with the patient. The procedures that are done are outpatient procedures that are in the office. The only time it’s done at a surgery center, again, as an outpatient procedure is if it involves a disc injection because those injections have to be performed with fluoroscopic guidance, which requires special equipment.

RC: Thank you so much, Dr. Bleiweiss. We know you’re busy, so I want to thank you for your time and your help today.

Dr. Warren Bleiweiss: You’re welcome.

RC: For our listeners across the country, if you are interested in speaking with the doctor, please visit www.alternativedisctherapy.com, or call 973-403-3334 to schedule an appointment.

On behalf of our team, we want to thank you for listening, and we look forward to bringing you more top-quality content from our country’s leading experts.

 

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Stem Cell Activating Treatments for Common Conditions

Stem Cell Activating Treatments for Common Conditions

How does regenerative medicine work? I am often asked of this question by my patients.

The body has an innate capacity to heal by replacing dying or injured cells and rejuvenating itself. We have this capacity at any age. The goal of regenerative medicine is to restore structure and function of a damaged tissue or an organ by using the body’s innate ability to heal. This is different from most modern medical treatment modalities which only manage conditions without any potential to actually heal. For example, if you have osteoarthritis and you take ibuprofen to reduce the pain and inflammation or you receive an injection into a joint with a compound such as a steroid or a lubricating agent.

Cellular and stem cell activating treatments are a very big and complex subject because the number of conditions that can be treated is vast. I would like to discuss just a few treatments that we perform as a starter and discuss more in future blogs.

Let’s start with osteoarthritis of the knee, hip or shoulder joints. As we age, we are all going to develop varying degrees of osteoarthritis of the joints. It is part of the aging process due to the normal wear and tear that our joints undergo as we go through life. Some people have it more in the hips, some people have it more in the knees, some people have it more in the hands, but it is a very common malady of humans. Regenerative medicine stem cell activating treatments are aimed at helping to restore structure and function, not just reducing inflammation or blocking pain receptors in the brain. That means that the joint is going to work better and it is not going to be as painful.

Let’s talk about hair loss which is a very common issue, particularly in men. It may not be a health issue, but it is something that bothers a lot of people. Regenerative medicine treatments can help hair follicles that are still alive to produce thicker hair and more hair. If the follicle is dead and totally gone, nothing is going to regrow a follicle. But, if the follicle is still there, even if one little tiny thin hair is coming out, regenerative medicine treatments can help that follicle produce thicker hair and more hairs out of the follicle.

Now, let’s talk about neurodegenerative conditions such as dementia and peripheral neuropathy. Both of these conditions can be improved by regenerative medicine treatments. Let’s take dementia today for example. One very common type of dementia is Alzheimer’s disease. Many doctors throughout the world have had excellent success in treating this condition with a regenerative medicine cellular treatment known as neuroregenesis. Though not a cure for the disease, noticeable and measurable positive outcomes usually occur. This treatment can address significant deterioration of brain dysfunction as well as with stages of forgetfulness. The treatment has been able to bring many people who are severely limited back into a more normal life and a more normal interaction with their families. It is also a useful treatment to help reverse aging related minor decline of brain function. For example, when someone feels as if their mind is not as sharp or quick as when they were younger, this regenerative medicine treatment can help.

The important thing to remember is that the goal of stem cell activating treatments is to restore structure and function of damaged tissues and organs. It works in part by the body’s innate ability to heal and rejuvenate. It is a very powerful and proven medical breakthrough.

PodCast: Cellular Treatments in Regenerative Medicine

Below you will find an easy to read transcript of Dr. Warren Bleiweiss’ podcast interview. You can listen to the podcast or simply read the easy to follow transcript below. Enjoy!

 

Podcast Interview:

RC: Hello everyone, this is Liz Harvey coming to you from our studios in New York City where we are dedicated to bringing you top quality advice from many of the leading expert professionals across the U.S.

In today’s episode, we are speaking with Dr. Warren J. Bleiweiss about the exciting field of regenerative medicine. He is a graduate of New York University School of Medicine and is Board Certified in both Anesthesiology and Pain Management.  His long list of accomplishments includes leadership experience as a hospital anesthesiology department director, the inventor of a patented medical device, and the founder of one of the first multi-disciplinary pain management centers in New Jersey.  

Dr. Bleiweiss also pioneered the treatment of oxygen-ozone disc injection therapy in the United States which is a powerful regenerative treatment. He has been successfully treating patients for over 30 years. Dr. Bleiweiss specializes in minimally invasive alternative treatments that heal patients without surgery or potentially harmful medications.  His treatment protocols are specifically designed to activate the body’s innate ability to recover and regenerate. His practice has been producing excellent results by utilizing these alternative methods.

We previously discussed oxygen-ozone treatments with Dr. Bleiweiss. Today we are focusing on other aspects of regenerative medicine and we are discussing cellular treatments in regenerative medicine.

Hello Dr. Bleiweiss, how are you today?

Dr. Warren Bleiweiss: I’m very well, thank you.

RC: Well, thanks for joining me again and I understand that you are very knowledgeable and up to date in the field of regenerative medicine.

Today, I would like to ask you about cellular treatments in regenerative medicine. Could you please give us a brief overview?

Dr. Warren Bleiweiss: Yes. I’d be very happy to. So, cellular treatments of regenerative medicine are typically known as stem cell treatments. So, for the purpose of this discussion, I’m going to use the phrase stem cell treatments. There are multiple safe sources of stem cells. To name a few, there are bone marrow stem cells, there are fat derived stem cells, and there are umbilical cord blood stem cells. Now, these cells have different qualities, but they act in very similar ways. And some of the ways that stem cells are very powerful healing agents in the body is that they have an ability to signal and activate stem cells that are present in our own body.

So, I want to take a step back and briefly discuss that the fact that we have a reservoir of stem cells in our body. When we’re young, these stem cells are very active and as we age, the stem cells become less plentiful and less active and there are also dormant stem cells. When we do stem cell treatments and we introduce new stem cells from whatever source, I’ve named a few, these stem cells will migrate to an injured structure or often we inject it directly into the injured structure or introduce it into the injured structure. The stem cells will sense the injury and send off signaling molecules that will activate dormant stem cells that we already have in our body. And those stem cells will follow the concentration gradients of these signals and actually migrate to the injured area. So, if the stem cells that we use are not only helping the cells that are injured, they’re also signaling for help from the other stem cells. It’s kind of like calling 911 if somebody’s injured and help arrived.

The stem cells have an extremely amazing ability to sense what an injured or damaged or dying cell needs and to provide that cell with what they need to nurse it back to health. All right, so I’ll elaborate. Let’s say an injured cell, we’ll talk about a joint. So, you have an injury in your joint and cartilage cells are injured and they’re dying. And if that continues, it becomes an arthritic condition that’s chronic which we call osteoarthritis. The stem cells will sense what these injured and dying cells need and excrete whatever it is, whether it’s a growth factor or another product that will help the cell heal. And the stem cells can also even donate their own mitochondria to an injured cell.

A mitochondria is the powerhouse of the cell. The mitochondria creates energy for the cell to live. Without a mitochondria, the cell cannot live. You could actually demonstrate this in a research laboratory that a stem cell will actually attach itself to an injured cell and donate its own mitochondria to that cell. So, these are just some small examples of how these cells will have powerful healing effects.

The bottom line is that all of our tissues have the capacity to regenerate and they just need the proper signals. Stem cells activate our own bodies’ repair system. So, for a patient, this means that we now have the ability to naturally restore structure and function of tissues and organs that are damaged by repeated trauma over time, stress, toxins, aging. All of these issues can damage structures in our body, whether it’s our skin, our hair, our lungs, our joints. This is how we treat it with stem cells.

What conditions can be treated with regenerative medicine using cellular treatments?

Dr. Warren Bleiweiss: There are many, many conditions that can be treated with stem cells. Listing every single treatment is definitely beyond the scope of this discussion because it would take a very long time. So, I’m just going to go over a few treatments. We already discussed osteoarthritis. Almost everybody on the planet as we age, develops osteoarthritis and can be of different joints. Some people have it worse in the knees. Some people have it worse in the hips, some people have it worse in the hands, it’s a common element. Stem cells are very effective in treating osteoarthritis. And again, as I mentioned before, this is a restoration procedure. This is a procedure that restores structure and function. We’re not just managing the condition, for example, with ibuprofen, with steroid injections, with lubricating injections; we’re not replacing the joint with metal, we’re restoring the structure and function of the joint.

Another condition that I mentioned is, as we age, a lot of us, unless we’re very lucky, especially men, start having thin hair and it turns out that stem cell treatments are very effective in inducing hair follicles to produce more hair and thicker hair.

As we age, we all get aging of the skin and stem cells are very, very good at rejuvenating the skin. Now they’re not going to get rid of all your wrinkles if you have wrinkles, but they’re definitely going to make your skin look and feel younger.

In conditions such as Alzheimer’s where there’s declining mental function, stem cells have been shown to be very effective. I believe we discussed this previously, I don’t want to give the impression that if someone has Alzheimer’s, you give them stem cells, they are going to be completely back to their normal self. I’m not making that representation, but they definitely will improve brain function to varying degrees in people with reduced brain function, especially if it’s picked up early and it hasn’t progressed to a very serious state. So, these are some of the conditions that are treated with stem cells.

How do you evaluate a patient to determine if they are a candidate for one of these procedures?

Dr. Warren Bleiweiss: Well, this is the most important step, the initial evaluation because first of all, if someone’s not a candidate, you don’t want to put someone through a treatment that they don’t need or will not likely benefit them. We don’t want to treat someone if there’s only a 50/50 chance of it helping. We want there to be a very significant chance of it helping, for example, 80%.

Also, there were so many different types of regenerative medicine treatments. Today we’re talking about cellular treatments, which as I stated before are commonly referred to as stem cells. There are varying types of stem cells, which we briefly went over. There are also a lot of non-cellular regenerative medicine treatments which I believe we’re going to discuss at a later time.

It’s very important for a physician to know which treatment is best for which patient. So, for example, I could treat a joint with stem cells and I could also treat a joint with non-cellular regenerative medicine treatments such as ozone. It depends on the joint condition. It depends on the individual. It depends on the goal of the treatment. All of these things are up to me to figure out in the initial evaluation and to determine what is best for the patient.

A lot of us refer to this as personalized precision medicine, because it’s personalized for the individual and it’s precise for that condition.

The history, the initial evaluation is the most important part as far as I’m concerned. I do all my initial evaluations. I don’t have anybody else doing it. I’m the person who does it. I do a careful history. I look at images. I look at laboratory tests. I might order some additional laboratory tests and I do a very careful physical examination and thorough for their condition. I mean, for example, if someone comes in with a joint condition, I’m not going to do an EEEG to evaluate their brain obviously. So that’s the most important step.

Could you walk us through what a typical patient would experience when they have a cellular regenerative medicine procedure?

Dr. Warren Bleiweiss: Yes, I’d love to. So again, I’d like to reiterate that these treatments are all about helping the body heal, regenerate and restore structure and function. It’s essential to assure that a patient is in optimal health to have the best chance of healing. I’m going to say that again because this is, I think, one of the most important issues. A patient’s body has to be in optimal health to have the best chance of success with these treatments. The reason why I repeated it twice is because I could go on the Internet and look up stem cell treatments and you’ll see advertisements and it says something like, “Have your consultation and your treatment on the same day and go home.” To me, that’s not an optimal treatment. That’s not the way I treat patients.

The very first thing, the most important thing as we already discussed is to do the initial evaluation because the initial evaluation is number one, going to tell me if a patient’s a good candidate for a procedure, number two, I’m going to determine which of the multiple procedures that are available are most likely to help that person. As I stated before, that’s why we call it personalized precision medicine or precision personalized medicine, however you want to say it. So that’s the most important first step.

The other thing that I want to point out is that a physician has to be well versed in performing all of these procedures because if I can’t perform procedure X and I could only perform procedure Y, if the patient needs procedure X, they’re not going to get procedure X from me. I mean, for me, I would send them out for procedure X, but in some instances, they might get procedure Y which is a good procedure, but it’s not the best procedure for them. So that’s the first step. Sometimes I’ll order additional specific laboratory tests to check out issues that I feel are important.

The next step is to prepare the body for the procedure. Now, preparing the body for the procedure involves nutritional guidance, vitamin supplements which we provide, a light exercise regimen, probiotics to help the gut health, which is very important because if you have a leaky gut and you’re getting toxins in your body, it’s going to negatively affect the stem cells. We encourage proper sleep, we encourage proper hydration. Now, this phase and the treatment is different for everybody. Remember I talked about personalized medicine.

Everybody is different. This phase could last a short time or it could last weeks. So for example, if someone comes in to see me and they injured their knee and they’re a 45-year old yoga instructor, they’re a vegan, they take vitamins every day for the last 30 years and they’re very healthy. That’s going to be a different preparation period than an average person like for example, me who tries to be healthy and tries to exercise, but I don’t always really keep up with it or I might cheat every once-in-a-while on what I eat and maybe have a little chocolate ice cream here and there, in a moment of weakness. So, I’m going to require a little more preparation than the 44-year old yoga instructor that’s been living healthy for their whole entire life. But again, this is personalized. It’s individual. I make that decision on how much preparation is needed.

Now, there’s an extra step for some specific procedures. So, if I’m injecting stem cells into a joint, I like to prepare the joint with oxygen ozone. Now it’s not done on the same day and I don’t want it to interfere with stem cells. But what the oxygen ozone does among many things, it helps with tissue oxygenation. It helps create optimal tissue oxygenation. And that’s not just because of the oxygen that’s in the oxygen ozone. It’s because of the blood flow to the tissues that’s induced by the oxygen-ozone injection. There are other benefits of oxygen ozone, which I don’t want to go into a very long discussion on. I’ve actually discussed it in the past in pretty extensive detail.

Then there’s the cellular treatment procedure, which is an outpatient office procedure. It is usually done under ultrasonic guidance. If it’s a disc injection, it has to be done in an outpatient center because I require a fluoroscopy machine, which is a large machine to do that procedure, but that’s also an outpatient procedure.

And the other thing that’s important is the post procedure care. I don’t just do the procedure and send the patient on their merry way. I want to see the patient for a follow up. I want the patient to continue taking various vitamins. I want the patient to know how to rehabilitate, let’s say it’s a joint. So what exercises do they have to do, how much pressure can they put on the joint? These are all very, very important things. So, it’s a protocol and it’s personalized for each individual.

RC: Okay. Well, thank you so much Dr. Bleiweiss. We know you’re busy, so I want to thank you for all of your time and your help today.

Dr. Warren Bleiweiss: You’re welcome.

RC: And for our listeners across the country, if you are interested in speaking with the doctor, please visit www.alternativedisctherapy.com or call 973-403-3334 to schedule an appointment.

And on behalf of our team, we want to thank you for listening and we look forward to bringing you more top-quality content from our country’s leading experts.

 

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Regenerative Medicine Treatments for Common Conditions

Regenerative Medicine Treatments for Common Conditions

Regenerative medicine works by harnessing our body’s innate ability to repair damaged tissue and to restore structure and function to damaged areas of the body.  A good example of this is the ability to treat an arthritic joint without surgery or harmful steroid injections.  These regenerative treatments are truly a game changer as compared with the standard tools and treatments of modern medicine.  For example, drug interventions such as ibuprofen, steroid injections or lubricating injections for joint pain are not healing the cartilage of the joint.  At best, they help manage the painful conditions or block the pain temporarily. These interventions do not address the root causes of the pain and have significant side effects.  This also applies to many other types of degenerative conditions such as spinal disc degeneration, hair loss or neuronal degeneration which can lead to memory problems.  Regenerative medicine on the other hand operates on a completely different principle. The goal of regenerative medicine is to help the body heal and thus enable the body to return as close as possible to its normal function and structure. The same principle applies to all of these structures.

Let’s use the same example of treating an injured or arthritic joint, such as the knee or hip joint.  A routine regenerative medicine treatment would be a stem cell activating guided joint injection procedure.  Stem cells have innate intelligence and the unique capacity to help in multiple ways.  For example, they will recognize the damage to the joint and initiate the healing process.

You might wonder how could stem cells recognize damage to a joint or organ?   It is actually an extremely fascinating and well researched phenomenon.  There is an innate intelligence in all aspects of our body and in any living organism, including single cells, to assess the local environment.   A single cell can sense chemical distress molecules that a damaged cartilage cell releases when it’s dying or injured.  Stem cells not only can sense those molecules and will be attracted to the damaged area, they can send out their own molecules to signal other stem cells from the reservoir of stem cells that everybody has in the body, to migrate into the damaged joint and help in the healing process. Stem cells can also excrete molecules that the weakened cell needs to nurse it back to health.  Stem cells can even donate mitochondria to damaged cells. Mitochondria are the powerhouse of the cells and are essential for cell life.  These are very powerful healing properties that stem regenerative medicine treatments have that can help to heal and restore structure and function.

To reiterate, our bodies have an innate ability to repair damaged tissue and heal at any age. Regenerative medicine activates this powerful healing ability of our body.

We discussed joints, now let’s talk about hair.   As we age, many of us start losing hair follicles.  They become less effective in producing hair, they produce thinner hair and eventually die.  Some of us are lucky enough not to have thinning hair, but it’s a very common issue that most people face.   Regenerative medicine is a powerful treatment that can potentially increase the amount of hair per follicle and the thickness of the hair.  If the hair follicle is completely dead, such as when the scalp is bald and there are absolutely no hair follicles, it’s not going to replace those hair follicles with new hair follicles.  But, in the initial stages of thinning hair when the hair follicles produce less  hair and thinner pieces of hair, the regenerative treatment has the significant potential to reverse the thinning process.

Another great treatment with regenerative medicine is to help improve brain function in patients with various dementia conditions such as Alzheimer’s.  Regenerative medicine helps to restore various neuronal interconnections and helps nourish various nerve cells back to health. It is not a cure for the condition and is not going to turn someone with dementia whose brain is severely compromised back into how they were when they were young.   However, it’s a very promising and exciting treatment with significant clinical evidence of slowing down and often improving memory loss.